One of the most complex discussions concerning climate emergency is the sustainable water management. How to deal with the risks generated by climate change where the presence of cultural and environmental assets is highly stratified over time? How to manage large densely populated areas rich in environmental and human resources, ensuring their protection and development? It’s now time to integrate the connections between the different territorial scales and to ensure the balance between public and private interests in a framework of sustainable strategies. SOS Climate Waterfront is an interdisciplinary project that aims to explore waterfronts in Europe that are facing climate change. The volume presents the results of the workshop held in Rome in spring 2022.